One way to think about what sugar does to our bodies is to imagine how it affects our pancreas. As sugar content in the blood goes up, the pancreas springs into action, since one of its jobs is to secrete insulin to balance blood sugar levels.
Simple sugars, simple carbohydrates, and high-glycemic index foods cause a rapid spiking in blood sugar, which demands a quick and equal response from the pancreas. Somewhat like the response at a fire station when a call comes for a building on fire. Another way to think of this is “Pancreatic Panic.”
Keep on eating sugars, over-taxing your pancreas, and at some point the pancreatic cells that secrete insulin begin to ‘wear out,” they begin to not work as well. This is part of how Type II Diabetes develops.