Once Upon a Time There Was Glycation

And it was found to be a big trouble-maker. Here’s the story: 

It is common that people with diabetes exhibit mental decline. Doctors & scientists noticed that the worse the hyperglycemia or erratic blood sugar, the greater the negative affect on mental capacity. They started wondering how sugar might be affecting the brain. 

They knew that neurodegenerative diseases like Alzheimer’s, Parkinson’s, and Lou Gehrig’s share something---deformed proteins in the brain. They also knew that deformed proteins, called prions, occur in the brain in Mad Cow Disease.

What was causing the deformation of these proteins?

Back in the early 1900’s something called the Maillard Reaction was discovered, in which sugar molecules spontaneously bond to proteins, fats, and amino acids. But it wasn’t until the 1980’s that this became revealing in trying to understand diabetic complications and aging.

The Maillard Reaction creates advanced glycation end products, or AGE’s, and these AGE’s include misshapen and deformed proteins. Glycated proteins hook up with other damaged proteins in cross-linkages, which worsens their dysfunction.

AGE’s are connected with aging in lots of ways—aging of our skin, kidney disease, damage to blood vessels, and mental decline. They stimulate inflammation throughout the body.

       It appears that if we want to keep our mental functions healthy as long as possible, one thing we can do is try to minimize the glycation of proteins. And that means reducing the availability of sugar.

Organic Farm & Garden, UCSC---50th Anniversary

       One of the country's oldest organic education and research programs, the Center for
Agroecology and Sustainable Food Systems (CASFS), with the University of CA Santa Cruz (UCSC) Organic Farm & Garden, will celebrate their 50th anniversary on July 28 - 30, 2017.

       The UCSC Farm & Garden has pioneered sustainable food production methods that are now widespread. More than 1500 graduates of the CASFS Apprenticeship Program have started their own farms, organic businesses, and food projects.        􀀰􀁉􀁏􀁎􀁅􀁅􀁒􀁅􀁄􀀀􀁏􀁒􀁇􀁁􀁎􀁉􀁃􀀀

      The weekend’s activities will be open to the public. There will be tours of the 30 acres of fields, orchards, & gardens; "food hero" speakers from the Sustainable Agriculture community; food & farming workshops; and a banquet featuring guest chef Alice Waters.

       For more information about this celebration & how you can participate, go to casfs.ucsc.edu, email casfs@ucsc.edu, or call (831) 459-3240.

Painfully Snapping "Trigger" Finger

       Fairly frequently in my office, a patient shows up with a painfully “snapping” finger, commonly referred to as a “trigger finger.” The condition also often occurs in the thumb.

       This is an inflammatory condition for which the technical term is "stenosing tenosynovitis."

       It occurs when inflammation causes a narrowing of the space around the finger’s (or thumb's) tendon and its surrounding tendon sheath. (The sheath is like a tube through which the tendon passes.) 

       My treatment includes adjusting the involved finger and teaching the patient to use an anti-inflammatory protocol at home. This includes antidotes to inflammation, such as ice, topical and / or systemic arnica, and nutritional support.  

       Protecting the involved finger to allow it to heal calls for splinting it to keep it from becoming stuck in a bent position, especially during the night. 

       Chiropractic adjustment of the involved finger with my Activator instrument is quick, precise, minimally uncomfortable, and brings immediate relief.  

Your Pain----Medicare Wants to Know About It

       Documentation about a patient’s condition is very important to Medicare, and caregivers, including Doctors of Chiropractic, are expected to ask the right questions. Information about your your pain, where it hurts, how badly it hurts, the type of pain you are having (is it sharp? achy, dull, burning, deep, etc.), is expected to be documented for Medicare at every office visit.

       In my office, Medicare patients fill out a brief Pain Report before every treatment. Questions include the level, or severity of pain, that day, on a scale of 1 - 10, with 10 being the worst. 

       The Pain Report also asks whether they felt relief after their last visit, and if so, for how long. They write down what they can do, or do better, since their last visit, and whether anything is still hard, or impossible, for them to do because of their pain.

Pesticides' Effects on Beneficial Insects & Other Organisms

Common pesticides, even those previously thought to be minimally harmful to human & environmental health, such as neonicotinoids, are being found to be dangerously toxic to honey bees, bumble bees, and natural parasites of crop pests. These include beneficial predatory and parasitic insects, such as “assassin” beetles & spotted lady beetles, which feed on harmful pests, providing natural pest suppression on farms.

Pesticides also affect the health of the soil. Residues of chemicals applied to crops can have harmful effects on earthworms and other soil invertebrates.

Perhaps pesticide use should be guided by the “Precautionary Principle”----stop using until we understand whether they cause undue harm to beneficial organisms.

http://xerces.org/2017/04/28/expanding-our-understanding-of-pesticide-impacts-on-invertebrates/

http://www.xerces.org/wp-content/uploads/2013/09/XercesSociety_CBCneonics_sep2013.pdf